What Other Information Should I Know
Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to minocycline.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking minocycline.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the minocycline, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
Common Side Effects Of Minocycline Vs Doxycycline
Minocycline and doxycycline each have a tendency to cause gastrointestinal side effects including nausea, vomiting, diarrhea, and anorexia. These side effects can be difficult to tolerate over longer periods of time and may be responsible for premature termination of therapy due to intolerability.
Minocycline has been associated with rare instances of liver failure and hepatitis. Patients with known hepatic impairment should avoid minocycline or be monitored closely while taking.
Doxycycline has been associated with the rare but serious adverse event of Stevens-Johnson syndrome. SJS may present with small purple or red spots, blisters, skin peeling, and/or rash. It is a very serious condition that requires immediate medical attention.
The following list is not intended to be a complete list of adverse events. Please consult a pharmacist, doctor, or another medical professional for a complete list of possible side effects.
| Minocycline |
Disadvantages Of Doxycycline For Sinus Infections
A major disadvantage with doxycycline use for sinus infection is its side-effect profile. The side-effects however are not very common and at the most to mild. Some patients may experience nausea, diarrhoea, vomiting and loss of appetite. Rarely do patients get headaches and alterations in their vision following doxycycline use but if they do occur, patients are strongly recommended to visit their health care practitioner with a view to stopping the treatment and taking a suitable alternative for the sinus infection.
Doxycycline for sinus infections in pregnant women is a contraindication meaning that it should not be prescribed for pregnant women.
Doxycycline is a useful antibiotic in the treatment of sinus infections.
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Effects Of Minocycline On Sci
Because the neuropathic pain and motor weakness that result from microglia activation are believed to trigger nociceptive hypersensitivity in SCI, minocycline could be a rational approach for treating the complications of this condition . Support for this proposition comes from the results of different studies that show that minocycline may reduce neuropathic pain after SCI. However, few data exist regarding minocyclineâs ability to promote motor recovery after SCI, rendering this possibility controversial. In rodent models of SCI, minocycline administration significantly improved both hindlimb function and strength, reduced the gross lesion size in the spinal cord and induced axonal sparing. Minocycline-treated mice demonstrated superior behavioural recovery than that shown by methylprednisolone-treated mice, the approved treatment for acute SCI in humans . In rats with SCI, minocycline inhibited the release of cytochrome c from the mitochondria, markedly enhancing long-term hindlimb locomotion . More recently, Saganováet al. showed that both short- and long-term treatment with minocycline had a neuroprotective effect on the spinal cord rostral to the injury epicentre. Previous data had indicated that minocycline exerts a protective effect on white matter and motor neuron number at sites both rostral, but also caudal, to the lesion epicentre .
How Should I Use This Medication
The usual recommended adult dose of minocycline is 100 mg or 200 mg for the first dose, followed by 100 mg every 12 hours. The adolescent dose of minocycline is based on body weight. Minocycline is not recommended for children under 13 years of age.
Do not take this medication at the same time as iron preparations or antacids that contain aluminum, calcium, or magnesium, since they may reduce the absorption of minocycline.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. Finish all of this medication, even if you start to feel better. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
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Composition Of Doxycycline For Sinus Infection
The medicine is sold under various brand names such as Oracea, Doryx, Monodox, Periosta and Vibramycin. The main ingredient of Doxycycline 100 mg Tablet is doxycycline Hyclate which belongs to the tetracycline class of drugs. This is derived from oxytetracycline. It can work against a wide variety of drugs hence, it is a broad-spectrum antibiotic.
What Side Effects Are Possible With This Medication
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.
The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- cramps or burning of the stomach
- diarrhea
- itching of the rectal or genital areas
- sore mouth or tongue
Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- abdominal pain
- yellowing of the skin
Stop taking the medication and seek immediate medical attention if any of the following occur:
- symptoms of a serious skin reaction
- symptoms of a severe allergic reaction
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
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Dosage Of Doxycycline For Sinus Infection
The medicine of Doxycycline is available in the following forms-
- Tablets
- Liquid form
- Intravenous solution
Doctors prescribe to take this medicine in the form of pills for people suffering from sinusitis. There are various strengths of Doxycycline for sinus infection- 50, 75, 100, and 150 mg. In order to take the medicine, theres no need to crush or break it. Take one tablet whole while drinking one full glass of water with each dose.
For adults-
Unless prescribed otherwise by doctors, usually the normal dose of oral form of doxycycline is 200 mg on the first day of the course. Followed by, changing the dosage to two 100 mg doses 12 hours apart. After this, maintaining a dose of 100 mg regularly for 7-10 days.
Although in rare cases, when the infection is severe, doctors can recommend higher doses such as 300 mg daily for 10 days.
For children-
Children over 8 years of age can take doxycycline for sinus infection. The dosage of the medicine depends on the childs weight.
Make sure that the course of the medicine is completed. Also, dont stop the medicine abruptly without proper consultation with the doctor.
When Does Antibiotic Resistance Occur
Antibiotic resistance occurs in a persons own body and within the community when certain drugs no longer work for a specific type of germ. This can occur when bacteria change in response to exposure to antibiotics so that the antibiotics no longer work efficiently against the bacteria.
Therefore, allergists and other specialists recommend limiting the use of antibiotics unless:
- Symptoms last over seven to 10 days
- Specific symptoms are present
- A fever is present
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Why Is Minocycline Bad For You
Minocycline is not necessarily bad, but it needs to be prescribed by a doctor for a specific number of days in order to treat the infection. Most antibiotics are only given for a short duration and then ceased once the patient starts to recover or shows complete recovery. This is done so that the bacteria dont become drug-resistant.
Which Drugs Or Supplements Interact With Minocycline
Minocycline should be used with caution with anticoagulant medications such as warfarin because it increases the risk of bleeding and bruising.
Antacids containing aluminum, calcium, magnesium and iron-containing medications can bind with minocycline, delay the absorption, and reduce the effectiveness of minocycline.
Minocycline should be used with caution with oral contraceptives because it may decrease the effectiveness of oral contraceptives.
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How Does This Medication Work What Will It Do For Me
Minocycline belongs to the class of medications called tetracycline antibiotics. It is used to treat infections caused by certain types of bacteria. It is most commonly used to treat certain types of skin infections, urinary tract infections, gallbladder infections, and respiratory tract infections such as bronchitis, pneumonia, and sinusitis.
This medication may be available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms or approved for all of the conditions discussed here. As well, some forms of this medication may not be used for all of the conditions discussed here.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
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Common Antibiotics For Sinus Infections
Antibiotics may be prescribed when symptoms of a sinus infection warrant such treatment. Common antibiotics for sinus infection include:
- Zithromax
- Levaquin : Although this drug is often prescribed as a first line of therapy for sinusitis, it has serious side effects and should only be used as a last resort.
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What Is The Most Important Information I Should Know About Minocycline
You should not take this medicine if you are allergic to minocycline or to similar antibiotics such as demeclocycline, doxycycline, or tetracycline.
If you are using minocycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.
Tell your doctor if you have ever had:
- liver disease
- kidney disease or
- asthma or sulfite allergy.
You should not use minocycline if you are pregnant. It could harm the unborn baby or cause permanent tooth discoloration later in life. Use effective birth control to prevent pregnancy while you are using this medicine, whether you are a man or a woman.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is taking minocycline. The use of this medicine by either parent may cause tooth discoloration later in the baby’s life.
Minocycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control to prevent pregnancy.
Minocycline passes into breast milk and may affect bone and tooth development in a nursing baby. You should not breast-feed while you are taking minocycline.
Do not give this medicine to a child without medical advice. Minocycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old.
Minocycline May Cause Side Effects Tell Your Doctor If Any Of These Symptoms Are Severe Or Do Not Go Away:
- nausea
- itching of the rectum or vagina
- changes in color of skin, scars, nails, teeth or gums.
- changes in color of tears or urine
- ringing in your ears
- inflammation of the end of the penis
- muscle pain
- a return of fever, sore throat, chills, or other signs of infection
- watery or bloody stools , stomach cramps, or fever during treatment or for up to two or more months after stopping treatment
- seizures
- chest pain or irregular heartbeat
Minocycline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s MedWatch Adverse Event Reporting program online or by phone .
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How Your Healthcare Provider Chooses
Your healthcare provider will only prescribe antibiotics for bronchitis if they think bacteria are causing your symptoms and youre at high risk of the infection not resolving on its own.
If a virus causes your bronchitis, they wont give you antibiotics because the antibiotics wouldnt do anything. If youre young and generally healthy, they probably wont prescribe anything either.
A Cochrane report last updated in 2017 found little evidence that antibiotics help acute bronchitis in healthy people, but recommended further study for patients that are elderly, frail, or have other conditions that may make bronchitis worse.
When considering treatment, your healthcare provider will look at:
- If youve had an allergic reaction to an antibiotic in the past
- Other health conditions, like autoimmune diseases, heart conditions, and lung conditions like asthma or chronic obstructive pulmonary disease
- Your history with smoking or vaping
- The oxygen levels in your blood
If your practitioner decides to prescribe an antibiotic, the treatment they choose will be based on your medical history, personal details, symptoms, diagnosis, and test results.
What Is A Sinus Infection Or Sinusitis
Inflammation of the air cavities within the passages of the nose is referred to as sinusitis. Sinusitis can be caused by infection , but also can be caused by allergy and chemical irritation of the sinuses. A sinus infection occurs when a virus, bacterium, or fungus grows within a sinus.
Sinusitis is one of the more common conditions that can afflict people throughout their lives. Sinusitis commonly occurs when environmental pollens irritate the nasal passages, such as with hay fever. Sinusitis can also result from irritants, such as chemicals or the use and/or abuse of over-the-counter nasal sprays, and illegal substances that may be snorted or inhaled through the nose. About 30 million adults have sinusitis. Colds differ from sinusitis and are only caused by viruses and last about seven to 10 days while sinusitis may have many different causes , and usually last longer with more pronounced and variable symptoms.
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Color Changes To Teeth
- Risk factors: Women in the last half of their pregnancy | Children age 8 or younger | Using minocycline for a long time or multiple times
Tetracycline antibiotics like minocycline can affect the teeth when they are still growing in young children. Usually, the teeth will permanently turn a yellow, gray, or brown color. Rarely, the teeth might not grow to be as strong because the enamel is also affected. This side effect can also happen to an unborn baby if the mother takes minocycline during the second half of her pregnancy. Pregnant women and young children shouldn’t take minocycline unless no other medications are available.
Can Minocycline Delay Your Period
Antibiotics are not usually known to delay periods. But that does not mean that your period will not be late. In fact, the stress of falling sick and suffering from a serious illness can lead to delayed menses in many women. If you feel your period has been unduly late, it is a good idea to consult a doctor for the same.
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Is Minocycline Or Doxycycline More Effective
The effectiveness of minocycline or doxycycline is relative to the indication being compared. One of the most common mutual indications for these two drugs is acne rosacea. A randomized controlled trial, published in 2017, sought to compare the efficacy and safety of these two drugs in the treatment of rosacea. Eighty patients with mild to severe rosacea were randomized to either doxycycline 40 mg or minocycline 100 mg. The results of the study found that improvement scores were significantly better for the minocycline group. The minocycline group also had fewer relapses in symptoms and had a longer remission period. There was no significant difference in safety between the two drugs.
A systematic review of literature was done to also compare and evaluate the safety and adverse events between minocycline and doxycycline. The review looked at 15 years of data. Doxycycline was prescribed three times more often than minocycline. While adverse events for either drug are relatively low, doxycycline was associated with fewer adverse events than minocycline.