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When you have a cold or an allergy attack, your white blood cells gather in your nasal passages and sinuses. This causes nasal membranes to swell and increases mucus production. Pseudoephedrine constricts these blood vessels, which decreases drainage.
But those same constricted vessels might also increase your blood pressure and heart rate.
Pharmacist Kayla Ryan explains the mechanism of pseudoephedrine. Pseudoephedrine is chemically similar to adrenaline, so the body recognizes it as adrenaline, causing the blood pressure and heart rate to increase.
She refers to one of the last major studies of the effects of pseudoephedrine on blood pressure, which took place in 2005. This study found that pseudoephedrine increased systolic blood pressure by one point on average, while heart rate increased by an average of three beats per minute.
Ryan adds that the immediate-release products had a greater impact on heart rate and blood pressure than their 12 hour or 24 hour extended-release counterparts, which showed a smaller increase in blood pressure.
In 2005, the FDA passed the Combat Methamphetamine Act, which requires pharmacies to sell all medications containing pseudoephedrine behind the counter. At your local drugstore, youll find cards in the cold and flu aisle with information for these medications. You can take the card to the pharmacist, who is required to scan your drivers license before purchase.
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Cold medicines are not off-limits if you have heart disease, but patients with high blood pressure, or hypertension, should check the label carefully when choosing a cold or allergy medicine.
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Thats because decongestants such as pseudoephedrine, ephedrine, phenylephrine, naphazoline and oxymetazoline can increase your blood pressure and heart rate. Make sure the cold or allergy medication you plan to take is free of those ingredients.
For allergy sufferers with heart disease, medicines such as Allegra, Zyrtec or Claritin should be safe. However, medicines containing decongestants including Allegra-D, Zyrtec-D and Claritin-D could increase your blood pressure and heart rate or interfere with your heart medication.
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Brands of common over-the counter decongestants that contain pseudoephedrine: Allegra-D, Alka Seltzer Plus Cold Medicine Liqui-Gels, Aleve Cold and Sinus Caplets, Benadryl Allergy and Sinus Tablets, Claritin-D Non-Drowsy 24 Hour Tablets, Robitussin Cold Severe Congestion Capsules, Sudafed 24 Hour Tablets, SudoGest, Wal-phed 12 hour, Suphedrine.2
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