Advil Cold And Sinus Dosage Adults

Are There Any Other Precautions Or Warnings For This Medication

Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Advil Cold & Sinus Side Effects

Get emergency medical help if you have signs of an allergic reaction or a severe skin reaction .

Get emergency medical help if you have signs of a heart attack or stroke: chest pain spreading to your jaw or shoulder, sudden numbness or weakness on one side of the body, slurred speech, leg swelling, feeling short of breath.

Stop using Advil Cold & Sinus and call your doctor at once if you have:

• confusion, severe drowsiness, ringing in your ears, severe dizziness, feeling like you might pass out

• fast, pounding, or uneven heartbeat

• easy bruising or bleeding

• a skin rash, no matter how mild

• signs of stomach bleeding–bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds

• liver problems–loss of appetite, stomach pain , tiredness, itching, dark urine, clay-colored stools, jaundice

• kidney problems–little or no urination, swelling in your feet or ankles, feeling tired or short of breath or

• nerve problems–fever, headache, neck stiffness, chills, increased sensitivity to light, seizure .

Common side effects may include:

What Are The Side Effects Of Ibuprofen/pseudoephedrine

With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.

Contact your doctor immediately if you experience any of the following:

• Heart attack: chest pain or tightness, pain that radiates up to your shoulder, arm, neck, or jaw
• Stroke: chest pain, trouble breathing, weakness in one part of your body or face, slurred speech, leg swelling
• Stomach bleeding: feeling faint, vomiting blood, bloody or dark stools, severe stomach pain or discomfort
• Allergic reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing, skin reddening

The following side effects may get better over time as your body gets used to the medication. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time.

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What Should I Watch For While Using This Medicine

Tell your doctor or healthcare provider if your symptoms do not start to get better or if they get worse. See your doctor if fever, pain, or nasal congestion gets worse or lasts more than 3 days.

If this medicine makes it hard for you to sleep, try taking the dose earlier in the day. If you still have trouble sleeping stop taking this medicine and see your doctor.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your healthcare provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

Advil Cold & Sinus Warnings/precautions:

Increased risk of severe stomach bleeding . History of GI disorders . Increased risk of heart attack or failure, and stroke. Hypertension. Heart disease. Recent stroke. Liver cirrhosis. Renal disease. Asthma. Thyroid disease. Diabetes. GI or urinary obstruction. Reevaluate if fever persists or worsens > 3 days or nasal congestion lasts > 7 days. Elderly. Pregnancy : not recommended. Nursing mothers.

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Ibuprofen Comparative Tolerability In A Large

In the PAIN study, published in Clinical Drug Investigation, overall tolerability of ibuprofen was:2,3

• Statistically equivalent to that of acetaminophen
• Superior to that of ASA

This large-scale randomized trial comparing nonprescription doses of ASA, acetaminophen, and ibuprofen in 8,677 adults measured rates of significant adverse events related to tolerability. The primary outcome measure was the number of patients with at least one significant adverse event, defined as an event that was serious, severe or moderate, resulted in a second physician consultation, led to cessation of treatment, or was of missing intensity. Statistical analysis tested for equivalence between ibuprofen and acetaminophen and for difference with ASA.2,3*

ASA = acetylsalicylic acid GI = gastrointestinal.* This was a blinded, multicentre study in general practice of up to 7 days of ASA, acetaminophen or ibuprofen , administered for common painful conditions, using patient generated data with physician assistance. 1,108 general practitioners included 8,677 adults . The main indications were musculoskeletal or back pain , sore throat, the common cold and flu .

Advil Sinus Congestion & Pain Interactions:

Hypertensive crisis with MAOIs. -blockers may increase the pressor effects of sympathomimetics. Caution with diuretics. Avoid aspirin, other pain relievers, nasal decongestants, or phenylephrine-containing products. Increased risk of GI bleed with anticoagulants, corticosteroids, other OTC or Rx NSAIDs, 3 alcoholic drinks/day, or prolonged use.

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What Is The Maximum Amount Of Ibuprofen In A Day

Advil can be taken by adults and children aged 12 years and over.

For adults and children aged 12 years and above, Advil Tablets/Liquid Capsules/Rapid Release Tablets include an equivalent of 200 mg of ibuprofen. For these products, it is recommended to take 1 to 2 tablets or capsules, swallowed whole with water. If necessary, repeat dose every 4-6 hours. Do not exceed 6 tablets or liquid capsules in 24 hours. For Advil 12 Hour Extended Release tablets, it is recommended to take 1 tablet swallowed whole with water. Do not split, crush or chew. If necessary, repeat dose after 12 hours. Do not exceed 2 tablets in 24 hours.

Advil products for children under 12 years have different recommended doses and maximum limits per day depending on the age and weight of the child. Please refer to the specific Advil Childrenâs product to determine the appropriate dosing for your child.

If You Are An Adult Over 60

• management or monitoring precaution: Cardiovascular-Elderly are more sensitive to tachycardia and hypertensive effects. May exacerbate symptomatic coronary insufficiency. Genitourinary-May cause urinary retention. Neuro/Psych-May worsen cognitive impairment in some elderly with dementia. Insomnia risk.
• management or monitoring precaution: Gastrointestinal-Risk for ulceration or serious GI bleed highest with history of PUD or GI bleed. Renal-Risk for exacerbation of CKD. Cardiovascular-May exacerbate pre-existing hypertension or CHF. Risk of cardiovascular thrombotic events, including MI and stroke. This risk may occur early in treatment and increases with duration of use. Risk for reinfarction with minimal NSAID use post-MI. Contraindicated with CABG. Hepatic-Elevated hepatic transaminases may occur with chronic use.

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Clinically Proven Efficacy In Sore Throat Pain

Ibuprofen offered statistically significant effective sore throat relief in the following study:

Clinical Pharmacology and Therapeutics, 1988

• A double-blind, single dose parallel study was conducted to evaluate treatment of sore throat pain. Ibuprofen was more effective on all rating scales from 180 to 360 minutes vs. acetaminophen and at all time points vs. placebo .14*

*Schachtel BP et al conducted a double-blind, single-dose parallel study of patients with tonsillopharyngitis who randomly received either 400 mg ibuprofen, 1000 mg acetaminophen or placebo. At hourly intervals for 6 hours, patients reported pain intensity and pain relief on conventional scales and two sensory qualities of throat pain on two new visual analogy scales.

How Can I Help Avoid Catching A Cold Or Flu

Here are some top tips to help you avoid getting a cold or flu:17

• Wash your hands regularly, especially after contact with others
• Avoid touching your nose and eyes, as they are the most common places for germs to get in
• Get enough sleep
• Exercise regularly to help enhance immune functions
• Avoid close contact with those who are experiencing cold and flu symptoms

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Hepatic And Renal Safety Profile

Clinical studies suggest that ibuprofen was associated with less acute liver injury compared to other NSAIDs:

Archives of Internal Medicine, 1994

• The lowest incidence of liver injury among 8 NSAIDs occurred in ibuprofen users and was 1.6/100000 . The other incidence in increasing order is as follows: oral diclofenac , naproxen , mefenamic acid , ketoprofen , piroxicam , fenbufen , sulindac 12

Postgraduate Medicine, 2018

• Compared to ibuprofen, risks of hepatoxicity are somewhat higher and better documented with acetaminophen, and reported to be higher amongst specific NSAIDs, such as oral diclofenac and sulindac13

Epidemiologic studies do not suggest that low dose ibuprofen is associated with an increased risk of renal adverse events

American Journal of Epidemiology, 2000

• Use of ibuprofen at 1200mg/day led to an odds ratio of 0.94 for renal AEs 9

Pharmacotherapy, 1999

• No major adverse events related to renal injury were identified during the study10

Pharmacotherapy, 1992

• After non-prescription doses of ibuprofen, renal injury were not amongst the reported adverse effects11

AE = adverse event CI = confidence interval GI = gastrointestinal NSAID = nonsteroidal anti-inflammatory drug OTC = over the counter.

How Should I Use This Medicine

Take this medicine by mouth with a glass of water. Follow the directions on the package label. You can take it with or without food. If it upsets your stomach, take it with food. Try to not lie down for at least 10 minutes after you take the medicine. Take your medicine at regular intervals. Do not take it more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years old for selected conditions, precautions do apply.

Patients over 65 years old may have a stronger reaction and need a smaller dose.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

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Pharmacist Tips For Ibuprofen/pseudoephedrine

Some people have a hard time sleeping after taking ibuprofen/pseudoephedrine because pseudoephedrine can cause insomnia. If you have a hard time falling asleep after taking this medication, take it earlier in the day and not too close to bedtime.

Stop using ibuprofen/pseudoephedrine and contact your provider if you have a fever that lasts more than 3 days, nasal congestion that lasts for more than 7 days, or if there is redness or swelling in a painful area. These might be signs of a serious infection or medical condition.

If you get nervous, dizzy, or can’t sleep, or if any new symptoms appear or your symptoms get worse, stop taking ibuprofen/pseudoephedrine. Contact your provider right away because these might be signs of a more serious medical condition.

Don’t start any new medications while taking ibuprofen/pseudoephedrine, especially other NSAIDs or decongestants, without talking to your provider or pharmacist first. Doing so can raise your risk of severe side effects, including stomach bleed, heart attack, stroke, or even death. Tell your provider or pharmacist about all the medications you’re taking to make sure ibuprofen/pseudoephedrine is safe for you.

Don’t take ibuprofen/pseudoephedrine if you’re taking or have taken an MAOI, such as selegiline or phenelzine , within the past 2 weeks. This combination can cause dangerous changes to your blood pressure. If you have taken an MAOI in the past 2 weeks, contact your provider for other options to treat your symptoms.

Worsening Of Medical Conditions

• Risk factors: History of serious side effects from other pain relievers | Stomach problems | Liver disease | Kidney disease | Heart disease or high blood pressure | Breathing problems | Thyroid disease | Diabetes | Glaucoma | Urinary conditions

Don’t take ibuprofen/pseudoephedrine if you have any of the risk factors listed above unless your provider said it is safe to do so. Taking ibuprofen/pseudoephedrine can worsen your condition and cause serious side effects. Make sure your provider knows about all medical conditions you have or have had in the past before starting ibuprofen/pseudoephedrine.

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What Side Effects Are Possible With This Medication

Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent.

The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.

• abdominal pain
• nervousness
• vomiting

Although most of the side effects listed below don’t happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

• blurred vision or other eye symptoms
• dizziness
• fluid retention
• ringing in the ears
• signs of clotting problems
• skin rash

Stop taking the medication and seek immediate medical attention if any of the following occur:

• signs of bleeding in the stomach
• symptoms of a severe allergic reaction

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

What May Interact With This Medicine

Do not take this medicine with any of the following medications:

• bromocriptine
• ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
• MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
• methotrexate

• steroid medicines like prednisone or cortisone
• St. John’s Wort

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

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How To Take Ibuprofen And Pseudoephedrine

Use Ibuprofen And Pseudoephedrine exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Use exactly as directed on the label, or as prescribed by your doctor. An overdose of ibuprofen can damage your stomach or intestines.

Take this medicine with food or milk to lessen stomach upset.

If you need surgery, tell the surgeon ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Since this medicine is used when needed, you may not be on a dosing schedule. Skip any missed dose if it’s almost time for your next dose. Do not use two doses at one time.

Can I Take Ibuprofen On Empty Stomach

The active ingredient in Advil is ibuprofen, an NSAID that is a pain reliever and fever reducer. It is not necessary to take Advil with food. However, it may help to take it with food or milk if an upset stomach occurs. Consult your doctor before taking any analgesic if you have a sensitive stomach or a history of stomach problems such as heartburn, upset stomach or stomach pain.

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How Should I Take Advil Cold & Sinus

Use exactly as directed on the label, or as prescribed by your doctor. An overdose of ibuprofen can damage your stomach or intestines.

Take Advil Cold & Sinus with food or milk to lessen stomach upset.

If you need surgery, tell the surgeon ahead of time if you have taken this medicine within the past few days.

Store at room temperature away from moisture and heat.

Does Ibuprofen Reduce Fever

The active ingredient in Advil is ibuprofen, an NSAID that is a pain reliever and fever reducer. Ibuprofen is the active ingredient in a range of over-the-counter medicines. Ibuprofen is classed as non-steroidal anti-inflammatory drug .

Body chemicals called prostaglandins produce pain and fever. Advil is an ibuprofen-based pain reliever brand that blocks the body’s production of these prostaglandins, therefore reducing pain and fever.

NSAIDs like ibuprofen are commonly used to manage mild to moderate pain , inflammation and fever in both adults and children.

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Ask A Healthcare Provider Before Use If

• You consume more than 3 alcoholic beverages a day. It may increase the risk of stomach bleeding
• You have heart disease
• You have trouble urinating due to an enlarged prostate gland
• You have had serious side effects from any pain reliever or fever reducer
• You are pregnant or breastfeeding. It may cause problems in an unborn child if taken during the third trimester of pregnancy

How Does This Medication Work What Will It Do For Me

This product is a combination of 2 medications: ibuprofen and pseudoephedrine. Ibuprofen is a nonsteroidal anti-inflammatory drug that reduces pain, fever, and inflammation by reducing a substance in the body that leads to inflammation and pain. Pseudoephedrine is a that relieves the symptoms of nasal and sinus congestion by reducing swelling in nasal passages and sinuses.

This medication is used to relieve nasal congestion, sinus congestion, sinus pain, fever, headache, sore throat, and body aches and pains that are associated with the common cold, sinusitis, or the flu.

Your doctor or pharmacist may have suggested this medication for conditions other than the ones listed in this drug information article. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor or pharmacist.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor or pharmacist has not recommended it.

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