Thursday, May 16, 2024

Can Metronidazole Treat Sinus Infection

What Drugs And Food Should I Avoid While Taking Metronidazole

How Effective Is Metronidazole for Urinary Tract Infection

While taking metronidazole and for 3 days after your last dose: Do not drink alcohol or consume foods, medicines, or other products that contain alcohol or propylene glycol. You may have unpleasant effects such as headaches, nausea, vomiting, stomach cramps, and warmth or tingling under your skin.

What Should I Know About Storage And Disposal Of This Medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light, excess heat and moisture .

It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.

Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.

What Are The Side Effects Of Cirpo Vs Flagyl

Cipro side effects

WARNING

Cipro and Cipro XR as well as other antibiotics in the fluoroquinolone class of antibiotics has been associated with tendonitis and even tendon rupture, particularly the Achilles tendon. Some doctors and other medical professionals recommend that their patients discontinue vigorous exercise while they are taking fluoroquinolone antibiotics.

Fluoroquinolones have neuromuscular blocking activity and can worsen muscle weakness in individuals with myasthenia gravis.

The most common side effects of Cipro, Cipro XR are:

Other serious side effects and adverse events of Cipro, Cipro XR include:

  • Cipro, Cipro XR should be used with caution in patients with central nervous system diseases such as seizures, because rare seizures have been reported in patients receiving Cipro, Cipro XR.
  • Cipro, Cipro XR should be avoided in children and adolescents less than 18 years of age, as safe use in these patients has not been established.
  • Many antibiotics, including Cipro, Cipro XR, can alter the normal bacteria in the colon and encourage overgrowth of a bacterium responsible for the development of inflammation of the colon, . Patients who develop signs of pseudomembranous colitis after starting Cipro, Cipro XR should contact their doctor immediately.

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What Decongestants And Nasal Sprays Soothe Or Cure Sinus Infections Or Sinusitis

Taking decongestants and mucolytics orally may be helpful in assisting drainage of sinus infection.

The treatment of chronic forms of sinus infection requires longer courses of medications, such as Augmentin, and may require a sinus drainage procedure. This drainage typically requires a surgical operation to open the blocked sinus under general anesthesia. In general, antihistamines should be avoided unless it is felt that the sinusitis sinus infection is due to allergies, such as pollens, dander, or other environmental causes.

It is likely that the use of a topical nasal steroid spray will help reduce swelling in the allergic individual without the drying that is caused by using antihistamines although both are occasionally used. Oral steroids may be prescribed to reduce acute inflammation and to help with chronic inflammation in cases with or without polyps and in allergic fungal sinusitis.

In many people, allergic sinusitis develops first, and later, bacterial infection occurs. For these individuals, early treatment of allergic sinusitis may prevent the development of secondary bacterial sinusitis.

In rare instances or in natural disasters, fungal infections may develop in debilitated people. Death rates of 50%-85% have been reported for patients with these sinus infections. Treatment relies on early diagnosis followed by immediate surgical debridement, antifungal drugs, , and stabilizing any underlying health problem such as diabetes.

Before Taking This Medicine

Will Flagyl Cure Gonorrhea

You should not use this medicine if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

  • you drank alcohol in the past 3 days

  • you consumed foods or medicines that contain propylene glycol in the past 3 days or

  • you took disulfiram within the past 14 days.

May harm an unborn baby. Do not use metronidazole to treat trichomoniasis during the first trimester of pregnancy. Tell your doctor if you become pregnant.

Not all uses of metronidazole are approved for treating children and teenagers. Metronidazole is not approved to treat vaginal infections in girls who have not begun having menstrual periods.

To make sure you can safely take this medicine, tell your doctor if you have ever had:

  • kidney disease

  • a heart rhythm disorder

  • a stomach or intestinal disease such as Crohn’s disease

  • a blood cell disorder such as anemia or low white blood cell counts

  • a fungal infection anywhere in your body or

  • a nerve disorder.

Metronidazole has caused cancer in animal studies. However, it is not known whether this would occur in humans. Ask your doctor about your risk.

You should not breastfeed within 24 hours after using metronidazole. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

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What Are The Dosages Of Metronidazole

Dosage of Metronidazole:

  • Loading dose: 15 mg/kg intravenously not to exceed 4 g/day
  • Maintenance dose: 7.5 mg/kg oral/intravenous every 6 hours x 7-10 days

Bacterial Vaginosis

  • 500 mg orally twice daily x 7 days, OR
  • 2 g orally once/day single dose, OR
  • Extended-release: 750 mg orally once/day x 7 days
  • 500 mg orally twice daily x 7 days, OR
  • 250 mg orally three times/day x 7 days
    • Prophylaxis start after mechanical bowel preparation the afternoon and evening before surgery
    • 1 g orally every 6-8 hours for 3 doses
    • 15 mg/kg IV over 30-60 min complete approximately 1 hour before surgery may administer 7.5 mg/kg IV over 30-60 min at 6 and 12 hours after initial dose for maintenance discontinue within 12 hours after surgery
    • Adult: 250 mg orally every 8 hours for 7 days alternatively, 375 mg orally every 12 hours for 7 days
    • 2 g orally once daily single dose alternatively, 1g orally every 12 hours for 2 doses
    • Pediatric: less than 45 kg body weight: 15 mg/kg/day IV/oral divided every 8 hours for 7 days not to exceed 2 g/day
    • Adult: 500-750 mg orally every 8 hours for 5-10 days
    • Pediatric: 35-50 mg/kg orally divided once every 8 hours for 10 days

    Gardnerella Infection

    Less than 1.2 kg

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    Intranasal Corticosteroids: Nonstandard Delivery

    Nonstandard topical corticosteroid delivery system, especially after sinus surgery, is an option in CRSwNP. General benefits are not available to statistically approve therapeutic recovery on existing evidence. Although evidence of adrenal suppression has not been seen, this cannot be ruled out by nonstandard delivery and dosing regimens. They have off-label use and possible minor side effects in comparison with oral corticosteroids .

    Has Levaquin Been Discontinued

    Antibiotic Choices for Common Infections: Antibiotics Mnemonic + How to Choose an Antibiotic

    Yes. In December 2017, Janssen Pharmaceuticals pulled Levaquin, the brand name of levofloxacin, and Floxin Otic, the brand name of ofloxacin ear drops, from production. Janssen said that it decided to discontinue Levaquin due to the broad availability of alternative antibiotics. However, there were several lawsuits over severe side effects caused by the antibiotic. These lawsuits came from Levaquin patients who experienced serious side effects, primarily aortic aneurysms and tendon ruptures, after taking the drug and claimed that Janssen Pharmaceuticals marketed the drug despite its potentially dangerous side effects.

    Prior to these lawsuits, the FDA had issued a black box warning for severe adverse effects linked to Levaquin, Cipro, Avalox, and other fluoroquinolones. A black box warning is the most serious type of warning the FDA will issue before completely banning a medication.

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    What Are Complications Of A Sinus Infection Or Sinusitis

    While serious complications do not occur frequently, it is possible for a sinus infection to cause a direct extension of infection into the brain through a sinus wall, creating a life-threatening emergency .

    In addition, other adjacent structures can become infected and develop problems, such as osteomyelitis of bones in the skull and infection around the eye . Rarely, these infections may cause death. The most susceptible individuals to complications are patients with suppressed immune systems, diabetes, and relatively rarely from multiple trauma injuries that may occur in natural disasters.

    Serious Side Effects And Complications

    Levofloxacin use has been linked to tendonitis and tendon rupture. These adverse effects may include symptoms such as bruising, tearing, and an inability to move the tendon area. Tendinitis and tendon rupture are most commonly in the Achilles tendon located at the back of the ankle, although they can also be experienced in the shoulder, hands, and other tendon areas. People who are over the age of 60, taking corticosteroid drugs, or have a history of kidney, lung, or heart transplants may be at an increased risk of tendonitis or tendon rupture while taking levofloxacin.

    Theres also a chance that levofloxacin can cause nerve damage in the arms, legs, hands, and feet, which manifests as pain, weakness, burning, tingling, or numbness. Central nervous system effects like seizures, lightheadedness, tremors, confusion, hallucinations, and severe headaches are possible serious side effects of levofloxacin.

    Levofloxacin may cause serious heart problems, such as QT prolongation and torsades de pointes. These heart rhythm problems may be characterized by a fast or irregular heartbeat.

    Some people who take levofloxacin may also experience a greater sensitivity to sunlight, leading to severe sunburn, blisters, and skin rashes after just a short time in the sun. While taking levofloxacin, avoid the sun if possible. If you are in the sun for a short period of time, wear sunscreen and clothes that cover the skin.

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    Intranasal Corticosteroids: Standard Delivery

    In the management of CRSwNP, the use of topical corticosteroids have keystone role. Intranasal corticosteroids are recommended before or after the surgery for CRSwNP. The use of INCS as sprays or drops have noteworthy benefits. Its advantages include improved symptoms, endoscopic views, size of polyp, quality of life, objective tests of smell, airway, and polyp relaps. Headache, epistaxis, and nasal mucosal damage may be seen as side effects .

    Will My Child Need To Go To Hospital

    How Long Does It Take For Metronidazole To Work?

    Your doctor will assess if you child should be looked after in hospital based on their symptoms and other factors, including their age. Babies under 6 months old are more likely to be admitted to hospital.

    Your doctor will take into account if your child:

    • has difficulty breathing
    • has low oxygen levels in their blood
    • is not responding to the prescribed antibiotics
    • has another lung, heart or immune deficiency condition

    In hospital your child may be given antibiotics through a drip. If they need it, they may be given oxygen to help them breathe more easily. If they are dehydrated, they may also be given fluids through a drip.

    When you must not take/use it

    Do not take/use Flagyl if you have ever had an allergic reaction to:

    • Flagyl or any other nitroimidazoles
    • Any of the ingredients listed here.

    Some symptoms of an allergic reaction include skin rash, itching, shortness of breath or swelling of the face, lips or tongue, which may cause difficulty in swallowing or breathing.

    Do not take/use Flagyl if:

    • You have evidence of, or have a history of, a blood disorder
    • You have, or have ever had, a disease of the brain, spinal cord or nerves
    • The expiry date on the pack has passed. If you take/use this medicine after the expiry date has passed it may have no effect at all, or worse, an entirely different effect
    • The packaging is torn or shows signs of tampering.

    If you are not sure whether to start taking/using Flagyl, talk to your doctor.

    Before you start to take/use it

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    Why Is This Medication Prescribed

    Metronidazole capsules and tablets are used to treat infections of the reproductive system, gastrointestinal tract, skin, heart, bone, joint, lung, blood, nervous system, and other areas of the body. Metronidazole capsules and tablets are also used to treat sexually transmitted diseases . Metronidazole extended-release tablets are used to treat bacterial vaginosis in women. Metronidazole is in a class of medications called nitroimidazole antimicrobials. It works by stopping the growth of bacteria.

    Antibiotics will not work for colds, flu, or other viral infections. Using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

    Which Side Effects Are Life

    All medications carry serious risks, including metronidazole, but thankfully they are very rare. These problems are more likely to happen if your dog is taking this medication at high doses or for a long time.

    Contact the emergency pet hospital right away if you notice any of the following:

    • Hives, fast heart rate, or trouble breathing signs of a possible allergic reaction

    • Changes to emotional behavior, such as seeming more depressed or lethargic than usual

    • Trouble walking, tremors, enlarged pupils, rapid eye movements or twitching, or seizures

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    What Is Cipro What Is Flagyl How Do They Work

    What Should I Discuss With My Healthcare Provider Before Using Metronidazole

    IBD School 307: Ciprofloxacin

    You should not use this medicine if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

    • you drank alcohol in the past 3 days
    • you consumed foods or medicines that contain propylene glycol in the past 3 days or
    • you took disulfiram within the past 14 days.

    May harm an unborn baby. Do not use metronidazole to treat trichomoniasis during the first trimester of pregnancy. Tell your doctor if you become pregnant.

    Not all uses of metronidazole are approved for treating children and teenagers. Metronidazole is not approved to treat vaginal infections in girls who have not begun having menstrual periods.

    Tell your doctor if you have ever had:

    • kidney disease
    • a heart rhythm disorder
    • a stomach or intestinal disease such as Crohn’s disease
    • a blood cell disorder such as anemia or low white blood cell counts
    • a fungal infection anywhere in your body or
    • a nerve disorder.

    Metronidazole has caused cancer in animal studies. However, it is not known whether this would occur in humans. Ask your doctor about your risk.

    You should not breastfeed within 24 hours after using metronidazole. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.

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    What Is The Dosage Of Cipro Vs Flagyl

    Cipro dosage

    • For most infections the recommended oral dose for adults is 250-750 mg every 12 hours or 500-1000 mg every 24 hours.
    • The usual intravenous dose is 200-400 mg every 8-12 hours.

    Flagyl dosage

    • Metronidazole may be taken orally with or without food.
    • In the hospital, metronidazole can be administered intravenously to treat serious infections.
    • The liver is primarily responsible for eliminating metronidazole from the body, and doses may need to be reduced in patients with liver disease and abnormal liver function.

    Various metronidazole regimens are used. Some examples are listed below.

    • Amebic dysentery: 750 mg orally 3 times daily for 5-10 days
    • Amebic liver abscess: 500-750 mg orally three times daily for 5-10 days
    • Anaerobic infections: 7.5 mg/kg orally or by injection every 6 hours for 7 to 10 days not to exceed 4 grams daily.
    • Bacterial vaginosis: 750 mg once daily for 7 days or 500 mg twice daily for 7 days or 2 g single dose or one applicator-full of 0.75% vaginal gel, once or twice daily for 5 days.
    • Clostridium difficile infection: 250-500 mg orally 4 times daily or 500-750 orally 3 times daily
    • Giardia: 250 mg orally three times daily for 5 days Helicobacter pylori: 800-1500 mg orally daily for several days in combination with other drugs.
    • Pelvic inflammatory disease : 500 mg orally twice daily for 14 days in combination with other drugs.
    • Trichomoniasis: 2 g single dose or 1 g twice
    • Rosacea: apply topical gel 0.75-1% once daily

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