What Are The Pros And Cons Of Doxycycline For A Sinus Infection
Doxycycline is a tetracycline antibiotic that fights infection-causing bacteria in the body. It is used for many different types of infections, including sinus infections, or sinusitis in severe cases. While taking doxycycline for a sinus infection may help clear the infection faster, the medication can cause side effects and might interact with other drugs and supplements.
In most countries, doxycycline requires a prescription from a doctor. When using doxycycline for a sinus infection, patients typically take 100 to 200 mg per day for seven to 10 days to help fight the infection. Its important for patients to take every dose exactly as recommended, even if they feel better before taking the full course of the medication. This helps prevent the infection from recurring. Both children over the age of eight and adults can take doxycycline, though a childs dose is typically lower than an adults and is based on weight.
What Is The Most Important Information I Should Know About Doxycycline
You should not take this medicine if you are allergic to doxycycline or other tetracycline antibiotics such as demeclocycline, minocycline, tetracycline, or tigecycline.
Tell your doctor if you have ever had:
- liver disease
- increased pressure inside your skull or
- if you also take isotretinoin, seizure medicine, or a blood thinner such as warfarin .
If you are using doxycycline to treat gonorrhea, your doctor may test you to make sure you do not also have syphilis, another sexually transmitted disease.
Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby. Taking doxycycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby’s life. Tell your doctor if you are pregnant or if you become pregnant.
Doxycycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control to prevent pregnancy.
Doxycycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breastfeed while you are taking doxycycline.
Doxycycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old. Children should use doxycycline only in cases of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever. The benefit of treating a serious condition may outweigh any risks to the child’s tooth development.
How To Use Doxycycline Hyclate Oral
This medicine is best taken by mouth on an empty stomach, at least 1 hour before or two hours following a meal, normally 1 or 2 times per day or as directed by your health care provider. Take this medicine with a complete glass of water unless directed differently. If stomach upset occurs, taking it with milk or food can help. But, doxycycline might not work too in the event that you take it with milk or food , so ask your doctor or pharmacist if you could take it like that.
Take this medicine 2-3 hours before or after taking any products containing magnesium, aluminum, iron, magnesium, zinc, or bismuth subsalicylate. Some instances include antacids, didanosine alternative, quinapril, vitamins/minerals, dairy products , and calcium-enriched juice.
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Doxycycline In Treating Patients With Chronic Rhinosinusitis With Nasal Polyps
| The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. |
| Recruitment Status : Terminated First Posted : October 6, 2015Results First Posted : January 9, 2018Last Update Posted : January 9, 2018 |
- Study Details
| Drug: DoxycyclineDrug: methylprednisoloneDrug: nasal saline sprayDrug: FlonaseDrug: sugar pill | Phase 2 |
| Study Type : |
| Triple |
| Primary Purpose: |
| The Role of Doxycycline in Management of Moderate to Severe Chronic Rhinosinusitis With Nasal Polyps |
| Study Start Date : |
0- Absence of nasal polyps
Usual Adult Dose For Acne
IV:-Initial dose: 200 mg IV on the first day, given in 1 or 2 infusions-Maintenance dose: 100 to 200 mg/day IVORAL:Most Products:-Initial dose: 200 mg orally on the first day, given in 2 divided doses -Maintenance dose: 100 mg orally once a day OR 50 mg orally every 12 hours—More severe infections : 100 mg orally every 12 hoursDoryx MPC:-Initial dose: 240 mg orally on the first day, given in 2 divided doses -Maintenance dose: 120 mg orally once a day or 60 mg orally every 12 hours—More severe infections : 120 mg orally every 12 hours
Read Also: Northwestern Sinus And Allergy Center
Basics Of Doxycycline For Sinus Infection
According to a clinical trial published in the National Library of Medicine, doxycycline was far more effective than ampicillin in curing sinusitis in affected patients. 90% of the patients responded to the drug while only 35% responded to ampicillin. It was inferred that this is effective as it fights against the organisms as well as can penetrate the sinuses which act as a reservoir for the infections.
Doxycycline is an antibiotic that cures a wide variety of infections caused by different bacteria. Apart from sinusitis, it can also cure other bacterial infections including urinary tract infections, respiratory infections, eye infections, gonorrhea, syphilis, etc.
In addition to these infections, medicine is very effective in treating skin blemishes or acne. Moreover, it is believed that taking this drug also reduces the risk of malaria.
What Drugs And Food Should I Avoid While Taking Doxycycline
Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking doxycycline.
Avoid taking any other antibiotics with doxycycline unless your doctor has told you to.
Doxycycline could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen when you are outdoors.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
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Who Needs Antibiotics Before Dental Work
Most patients don’t require antibiotics before dental work. Immune systems are more than capable of handling these bacteria, but there are some people who may need antibiotics after oral surgery. This may include those have had or have:
- Heart conditions, including congenital heart defects and disease
- An artificial heart valve
- Knee or hip replacement surgery
- Diabetes
- Cancer
- Infective endocarditis
Always make sure to share your full medical history with your doctor before surgery or dental work, even if you think it’s not relevant, so they know if they need to prescribe antibiotics before or after dental work.
Composition Of Doxycycline For Sinus Infection
The medicine is sold under various brand names such as Oracea, Doryx, Monodox, Periosta and Vibramycin. The main ingredient of Doxycycline 100 mg Tablet is doxycycline Hyclate which belongs to the tetracycline class of drugs. This is derived from oxytetracycline. It can work against a wide variety of drugs hence, it is a broad-spectrum antibiotic.
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Disadvantages Of Doxycycline For Sinus Infections
A major disadvantage with doxycycline use for sinus infection is its side-effect profile. The side-effects however are not very common and at the most to mild. Some patients may experience nausea, diarrhoea, vomiting and loss of appetite. Rarely do patients get headaches and alterations in their vision following doxycycline use but if they do occur, patients are strongly recommended to visit their health care practitioner with a view to stopping the treatment and taking a suitable alternative for the sinus infection.
Doxycycline for sinus infections in pregnant women is a contraindication meaning that it should not be prescribed for pregnant women.
Doxycycline is a useful antibiotic in the treatment of sinus infections.
What Is The Best Antibiotic For Tooth Infection Treatment
In many cases, antibiotics from the penicillin class, including penicillin and amoxicillin, are the best antibiotics for tooth infection. But that doesn’t mean these are the right choices for everyone! In fact, antibiotics may not be what you need even If you have a tooth infection.
You should never take an antibiotic without a prescription from your dentist or doctor. Many people take antibiotics without a prescription, and this is leading to antibiotic resistance in bacteria.
That means that some bacterial infections can no longer be treated with antibiotics which is a scary thought!
Instead of antibiotics, your dentist may decide that the best course of action is to drain your abscess, perform a root canal, or possibly remove the infected tooth.
That being said, you are more likely to receive antibiotics for a tooth infection when your infection is severe and spreading or if you are an individual with a weakened immune system.
The best antibiotic for a tooth infection will depend on the type of bacteria that is causing your infection and the location of your infection. That’s because different classes of antibiotics work in different ways to fight bacteria.
This is one of the reasons why it’s essential to take the antibiotic exactly as prescribed by your dentist until you’ve finished your prescribed course of treatment. Your dentist or doctor will know which is the best drug to take for your infection based on your medical history and the type of infection.
Also Check: Why Do I Get Sinus Infections So Often
Can I Take Doxycycline If Im Pregnant Or Breastfeeding
Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby. Taking doxycycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby’s life. Tell your doctor if you are pregnant or if you become pregnant.
Doxycycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control to prevent pregnancy.
Doxycycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breastfeed while you are taking doxycycline.
Doxycycline Capsules Bp 100mg
This information is intended for use by health professionals
DOXYCYCLINE CAPSULES BP 100mg
Each capsule contains Doxycycline hyclate equivalent to 100mg of Doxycycline base.
For the full list of excipients, see section 6.1.
Green hard gelatin capsules printed C and DW in black.
Doxycycline has been found clinically effective in the treatment of a variety of infections caused by susceptible strains of Gram-positive and Gram-negative bacteria and certain other micro-organisms.
Respiratory tract infections: Pneumonia and other lower respiratory tract infections due to susceptible strains of Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae and other organisms. Mycoplasma pneumoniae pneumonia. Treatment of chronic bronchitis, sinusitis.
Urinary tract infections: caused by susceptible strains of Klebsiella species, Enterobacter species, Escherichia coli, Streptococcus faecalis and other organisms.
Sexually transmitted diseases: Infections due to Chlamydia trachomatis including uncomplicated urethral, endocervical or rectal infections. Non-gonococcal, urethritis caused by Ureaplasma urealyticum . Doxycycline Capsules are also indicated in chancroid, granuloma inguinale and lymphogranuloma venereum . Doxycycline is an alternative drug in the treatment of gonorrhoea and syphilis.
Skin infections: Acne vulgaris when antibiotic therapy is considered necessary.
Doxycycline is an alternative drug in the treatment of leptospirosis, gas gangrene and tetanus.
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How To Use Doxycycline Calcium Syrup
Read the Patient Information Leaflet if available from your pharmacist before you start taking doxycycline and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
This medication is best taken by mouth on an empty stomach, at least 1 hour before or 2 hours after a meal, usually 1 or 2 times daily or as directed by your doctor. Take this medication with a full glass of water unless directed otherwise. If stomach upset occurs, taking it with food or milk may help. However, doxycycline may not work as well if you take it with food or milk , so ask your doctor or pharmacist if you may take it that way. Do not lie down for at least 10 minutes after taking this medication.
Take this medication 2 to 3 hours before or after taking any products containing aluminum, calcium, iron, magnesium, zinc, or bismuth subsalicylate. Some examples include antacids, didanosine solution, quinapril, vitamins/minerals, dairy products , and calcium-enriched juice. These products bind with doxycycline, preventing your body from fully absorbing the drug.
When using to prevent malaria, this medication is usually taken once daily. Take the first dose of this medication 1 to 2 days before travel or as directed by your doctor. Continue to take this medication daily while in the malarious area. Upon returning home, you should keep taking this medication for 4 more weeks. If you are unable to finish this course of doxycycline, contact your doctor.
Dosage Of Doxycycline For Sinus Infection
The medicine of Doxycycline is available in the following forms-
- Tablets
- Liquid form
- Intravenous solution
Doctors prescribe to take this medicine in the form of pills for people suffering from sinusitis. There are various strengths of Doxycycline for sinus infection- 50, 75, 100, and 150 mg. In order to take the medicine, theres no need to crush or break it. Take one tablet whole while drinking one full glass of water with each dose.
For adults-
Unless prescribed otherwise by doctors, usually the normal dose of oral form of doxycycline is 200 mg on the first day of the course. Followed by, changing the dosage to two 100 mg doses 12 hours apart. After this, maintaining a dose of 100 mg regularly for 7-10 days.
Although in rare cases, when the infection is severe, doctors can recommend higher doses such as 300 mg daily for 10 days.
For children-
Children over 8 years of age can take doxycycline for sinus infection. The dosage of the medicine depends on the childs weight.
Make sure that the course of the medicine is completed. Also, dont stop the medicine abruptly without proper consultation with the doctor.
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Algorithm For Use Of Antibiotics In Acute Sinusitis
|
Adapted from Chow AW, Benninger MS, Brook I, et al: IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults. Clinical Infectious Diseases 54 :10415 . |
In exacerbations of chronic sinusitis in children or adults, the same antibiotics are used, but treatment is given for 4 to 6 weeks. The sensitivities of pathogens isolated from the sinus exudate and the patients response to treatment guide subsequent therapy.
Sinusitis unresponsive to antibiotic therapy may require surgery to improve ventilation and drainage and to remove inspissated mucopurulent material, epithelial debris, and hypertrophic mucous membrane. These procedures usually are done intranasally with the aid of an endoscope. Chronic frontal sinusitis may be managed either with osteoplastic obliteration of the frontal sinuses or endoscopically in selected patients. The use of intraoperative computer-aided surgery to localize disease and prevent injury to surrounding contiguous structures has become common. Nasal obstruction that is contributing to poor drainage may also require surgery.
What Is Doxycycline
Doxycycline is an antibiotic used to treat bacterial infections, such as of the chest, sinus, eye and pelvic infections. It may be chosen if you are allergic to penicillins. Doxycycline is also used to treat skin conditions such as acne and for malaria prevention when travelling to some countries.Doxycycline belongs to a group of antibiotics called tetracyclines. Like all antibiotics, doxycycline is not effective against infections caused by viruses. In New Zealand, doxycycline is available as tablets .
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How Does It Work
It gets absorbed by oral administration. This medicine works by restricting the formation of bacterial protein. This happens by binding certain units of the protein. This stops the protein from growing and treats the infection.
Note: Keep the medicine at room temperature in a cool and dry place. Keep it away from the reach of children.
Doxycycline For Upper Respiratory Infection
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What Is The Dosage Of Amoxicillin Vs Doxycycline
Amoxicillin
- For most infections in adults the dose of amoxicillin is 250 mg every 8 hours, 500 mg every 8 hours, 500 mg every 12 hours or 875 mg every 12 hours, depending on the type and severity of infection.
- For the treatment of adults with gonorrhea, the dose is 3 g given as one dose.
- For most infections, children older than 3 months but less than 40 kg are treated with 25 or 45 mg/kg/day in divided doses every 12 hours or 20 or 40 mg/kg/day with one-third of the daily dose given every 8 hours depending on the type and severity of the infection.
- Amoxicillin can be taken with or without food.
Doxycycline
- The absorption of doxycycline is not markedly affected by food, and therefore, it can be taken with meals.
- For most infections, doxycycline is taken once or twice daily for 7 to 14 days.
- For adult infections, the usual dose of oral doxycycline is 200 mg on the first day of treatment followed by a dose of 100 to 200 mg/day as a single dose or divided and administered twice daily.